Buffalo Evolutionary and Anthropological Genomics Laboratory
Investigating the evolutionary history of genetic variations to explain biological diversity and disease in modern and ancient human populations.
WHAT WE DO
We investigate the contributions of genomic structural variations (rather than single nucleotide variations) to human evolution, combining tools from genomics, functional genetics, anthropology, and evolutionary biology to mechanistically link genetic variation to phenotypic diversity.
RESEARCH INTERESTS
OUR WORK
Our latest publications
Human subsistence and signatures of selection on chemosensory genes
Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity
A mechanism of gene evolution generating mucin function
Similarity-Based Analysis of Allele Frequency Distribution among Multiple Populations Identifies Adaptive Genomic Structural Variants
Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva
Data and Code
Visit our GitHub repo for codes, applications, and datasets. The links to primary datasets can be found in the relevant publications.