Buffalo Evolutionary and Anthropological Genomics Laboratory (BEAGL)
Investigating the evolutionary history of genetic variations to explain biological diversity and disease in modern and ancient human populations.
WHAT WE DO
We investigate the contributions of genomic structural variations—beyond single nucleotide variations—to human evolution, combining tools from genomics, functional genetics, anthropology, and evolutionary biology to mechanistically link genetic variation to phenotypic diversity.
RESEARCH INTERESTS
OUR WORK
Our latest publications
Deciphering the role of structural variation in human evolution: a functional perspective
Emergence of saliva protein genes in the secretory calcium-binding phosphoprotein (SCPP) locus and accelerated evolution in primates
Ancient AMY1 gene duplications primed the amylase locus for adaptive evolution upon the onset of agriculture
Gene communities in co-expression networks across different tissues
Genomic evidence for ancient human migration routes along South America’s Atlantic coast
Data and Code
Visit our GitHub repo for codes, applications, and datasets. The links to primary datasets can be found in the relevant publications.