New paper: Of archaic admixture in Africa, cherries, and serendipity

We have a new paper -two years in the making - where we showed evidence for introgression from an African archaic hominin to the ancestors of modern humans. This is a relatively big and, I have to admit, a serendipitous finding, corroborating the emerging notion that an "interbreeding bonanza" has shaped our ancestors. I do … Continue reading New paper: Of archaic admixture in Africa, cherries, and serendipity

New paper: Evolutionary history of a common psoriasis associated deletion

Following up our earlier insights into "ancient" human deletion polymorphisms that are shared with Neanderthals or Denisovans, we published a paper in BMC Evolutionary Biology, describing a small, but neat example of likely balancing selection acting on a large, common and psoriasis-associated deletion in humans. The haplotype that harbors this deletion show unusually high variation and an … Continue reading New paper: Evolutionary history of a common psoriasis associated deletion

First paper from our lab – Ancient deletions strike again and mysterious ways of adaptive forces

We have our first paper from the Buffalo laboratory published at Molecular Biology and Evolution (link here, it is Open Access). The paper describes polymorphic human deletions that are shared with Neandertals or Denisovans. Most of these deletions are not introgressed from ancient hominins, but rather have been lingering around since before Human/Neandertal/Denisovan ancestor. As expected majority … Continue reading First paper from our lab – Ancient deletions strike again and mysterious ways of adaptive forces

Our group is now affiliated with Institute for European and Mediterranean Archaeology

We are now officially affiliated with Institute for European and Mediterranean Archaeology, which involve multidisciplinary research and many outstanding colleagues. This is a pretty nice framework for students that want to undertake anthropological fieldwork and archaeogenetics research. Also, very interesting and high-profile international seminar series is a plus.

T24 Söyleşisi

T24'de genetik çeşitlilik üzerine bir söyleşi yaptık Hazal Özvarış ile. Biraz dallanıp budaklansa da, sanıyorum bazı ana temaları isabetli bir şekilde sunabildik. Söyleşiye buradan ulaşabilirsiniz. Bu vesile ile Ekşi Sözlük'te yerimi almış oldum. 🙂

New paper in PLoS Genetics – Balancing Selection shaping the distribution of a common deletion variant

Finally, our manuscript entitled "Balancing selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence" was published in PLoS Genetics. You can find it here... It is Open Access. Also, link to the post regarding the manuscript in Dienekes' Anthropology Blog. Note the several interesting points that commentators were raising. Another recent blog post … Continue reading New paper in PLoS Genetics – Balancing Selection shaping the distribution of a common deletion variant

Bilim kazanında günün kepçesi oldum

Bilim kazanı için İlker ve Aysu ile uzunca bir muhabbet ettik. Tatlı dillerinden ayrılıp da eve dönmem gece yarısı 1'i buldu. Ama galiba ayırdığımız 5 saate değdi. İnsanı insan yapan nedir diye sorduk - Dinlemek için basın buraya. Bu arada iyice yaşlandığımı tasdikleyecek ama, FatBoy Slim'in şu klibini hatırlamadım değil... 🙂 https://www.youtube.com/watch?v=ub747pprmJ8  

Ancient DNA from Anatolia

I was a co-author in an article, which made an initial attempt to look into the genetic structure in ancient Anatolia. If you are interested: Understanding Early Bronze Age social structure through mortuary remains: A pilot aDNA study from Titriş Höyük, southeastern Turkey