A new review paper by the mighty @marie_saitou on the difficulties and promises in integrating evolutionary framework and investigation of genomic structural variants. We talk a lot about how structural variants of different types likely
We have reported a computational method to detect the haplotypes harboring polymorphic gene duplications in the human genome variation dataset. This study is now published in Genome Biology and Evolution. The maestro (is it maestra?),
Stefan (Ruhl) and I recently published a comprehensive survey of the amylase gene copy number and salivary enzyme activity among mammalian species eLife. Petar (Pajic) was the driving force for the sample collection and analysis.
Onta (Yen Lung Lin) led the charge in this careful characterization of regions in the genome where that lead to the recurrent formation of structural variation. The paper “Fine-scale characterization of genomic structural variation in
A whole gene deletion sounds awful! You lose one entire gene and hence the protein that this gene is coding. However, there exist several gene deletions which have been maintained polymorphically among human populations. In
An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence Press release by Charlotte Hsu Academic minute podcast by our collaborator Ekin Atilla The evolution of cellular senescence is a remarkable question. It
I am pleased to announce that the online version of the Special Issue in Human Biology which I edited has now come out. It represents, in my opinion, the best examples of the new and
Erica (Duo Xu) has spearheaded an effort to compile all the small, different methods that we developed for analyzing population genomics data to construct locus-specific phylogenies into a streamlined pipeline. Yousef Jaber, a bright undergrad
We have a new paper -two years in the making – where we showed evidence for introgression from an African archaic hominin to the ancestors of modern humans. This is a relatively big and, I
I wanted to write this post to discuss an interesting discussion going on with regards to evolutionary basis of human complex diseases. It stems from our paper that looked into the evolution of skin barrier related
We have helped Cemali Bekpen and the Max Planck Evolutionary Biology Group of Dr. Tautz in resolving a very complicated and variable gene duplication. Even though, some of the trends remain fuzzy, it is now
