New paper: Of archaic admixture in Africa, cherries, and serendipity

We have a new paper -two years in the making - where we showed evidence for introgression from an African archaic hominin to the ancestors of modern humans. This is a relatively big and, I have to admit, a serendipitous finding, corroborating the emerging notion that an "interbreeding bonanza" has shaped our ancestors. I do … Continue reading New paper: Of archaic admixture in Africa, cherries, and serendipity

New paper: Of light, duplications and UV protection

We have helped Cemali Bekpen and the Max Planck Evolutionary Biology Group of Dr. Tautz in resolving a very complicated and variable gene duplication. Even though, some of the trends remain fuzzy, it is now clear that gene duplications of SPATA31 diversified in humans and remain variable. What is more, some of their function has to do … Continue reading New paper: Of light, duplications and UV protection

New Paper: Lipids and transcripts within the context of cellular senescence

We now published a paper with Atilla Lab describing the systems level analyses of lipidome and transcriptome as the cells age (i.e., as they stop dividing). Our results highlight the multiple roles of different lipid families are playing in this cellular process. The paper got published in Molecular Biosystems - Here is the link (behind a pay-wall unfortunately). … Continue reading New Paper: Lipids and transcripts within the context of cellular senescence

New paper: Evolutionary history of a common psoriasis associated deletion

Following up our earlier insights into "ancient" human deletion polymorphisms that are shared with Neanderthals or Denisovans, we published a paper in BMC Evolutionary Biology, describing a small, but neat example of likely balancing selection acting on a large, common and psoriasis-associated deletion in humans. The haplotype that harbors this deletion show unusually high variation and an … Continue reading New paper: Evolutionary history of a common psoriasis associated deletion